I'm looking for...
close

Did you know that your Internet Explorer is out of date?

To get the best possible experience using our website we recommend that you upgrade to a newer version or download another web browser.
A list of the most popular web browsers can be found below. Just click on the icons to get to the download page.

crome
Google Chrome		 IE
Internet Explorer		 firefox
Mozilla Firefox		 opera
Opera

Your browser will need to close to complete the installation and you will need to manually reload the site when finished
Hot Science Jobs
Senior Electrical Engineer
Galway
Quality Engineer
Galway
Purchasing & Planning Manager
Wexford
Quality Manager
Dublin
Principal R&D Engineer
Galway
Senior Operations Engineer
Galway
R&D Manager
Galway
Regulatory Affairs Manager- Remote
Republic of Ireland
Quality Engineer
Athlone
Product Development Manager
Galway
R&D Manager
Athlone
Senior Manufacting Engineer
Republic of Ireland
R&D Engineer
Dublin
Project Manager - New Product Introducti
Dublin
Design Quality Engineer
Galway
Principal R&D Engineer
Galway City
R&D Manager
Connaught
Senior Product Development Engineer
Galway
Product Development Technician II
Galway
Quality Specialist
Clare
Project Manager
Kildare
Documentation Specialist
Louth
Construction Manager - Pharma/Biotech
Dublin
R&D Engineer
Galway
Product Development Engineer II
Athlone
Product Specialist (Endoscopy)
Dublin
Supply Chain Project Manager (hybrid)
Dublin
Sr Project Manager - Syringe Fill Engine
Dublin
Senior R&D Engineer
Galway
Senior R&D Engineer
Galway
R&D Engineer
Galway
Dental- Manager/ Senior Manager Business
Republic of Ireland
Quality Control NPI Specialist
Carlow
Senior Equipment Design Engineer
Dublin
R&D Technician II
Galway
Tech Transfer Lead - Sterile Drug Produc
Dublin
R&D Engineer
Clare
Regulatory Affairs Maanger
Galway
R&D Engineer
Galway
R&D Manager
Athlone
Quality Manager
Galway
Senior R&D Engineer
Dublin
Senior R&D Engineer
Galway
Dental- Manager/ Senior Manager Business
Republic of Ireland
Commercial Attribute Science Scientist
Dublin
Process Chemist
Limerick
Senior NPI Engineer - Hybrid
Dublin
Principal Design Assurance Engineer
Galway
Senior R&D Engineer II
Galway
Director of Regulatory Affairs
Galway
CTO
Dublin
Senior R&D Manager
Athlone
Senior Design Assurance Engineer
Galway
Key Account Manager (Retail & Pharm
Dublin
Responsible Person (RP)
Republic of Ireland
R&D Engineer
Galway
Strategic Automation Lead
Waterford
Regulatory Affairs Specialist
Cork
Purchasing & Planning Manager
Wexford
Principal R&D Engineer
Dublin
Project Manager (Pharma)
Dublin
Quality Assurance Specialist (shift)
Carlow
Senior Equipment Design Engineer
Dublin
Process Engineer
Carlow
R&D Manager
Galway
Senior Regulatory Affairs Specialist
Athlone
Principal R&D Engineer
Dublin
CQV Engineer
Dublin
Senior Quality Engineer
Dublin
Commercial Solutions Manager (Medical De
Dublin
R&D Senior Program Manager
Galway
R&D Manager
Galway
R&D Lifecycle Manager
Connaught
Senior Regulatory Affairs Specialist
Clare
Senior Mechanical Engineer
Dublin
Project Engineer
Roscommon
Validation Engineer
Athlone
Health & Safety Specialist
Louth
Senior Regulatory Affairs Specialist
Athlone
QA Engineer
Leitrim
Quality Manager
Galway
Senior Research and Development Engineer
Galway
Senior Maintenance Technician
Kilkenny
Senior Process Engineer
Longford
Senior R&D Engineer-New Product Deve
Westmeath
Quality Technician
Dublin
R&D Manager
Connaught
Product Specialist (Critical Care &
Dublin
R&D Engineer
Galway
Senior Regulatory Affairs Specialist
Athlone
Technical Transfer Specialist - Remote
Republic of Ireland
Sterilisation Manager
Tipperary
Senior Electronic Engineer
Dublin
Manufacturing Technician
Clare
Design Assurance Program Manager
Galway
Sterilisation Manager
Tipperary
Graduate Occupational Hygiene Consultant
Kildare
Documentation Specialist
Louth
Principal R&D Engineer
Galway
R&D Technician II
Galway
Business Development Manager
Republic of Ireland
Electrical Condition Monitoring Technici
Limerick
Senior Design Engineer
Dublin
R&D Director
Galway
Pharmacovigilance Manager (Remote)
Republic of Ireland
Injection Moulding Engineer
Athlone
R&D Manager
Dublin
Validation Engineer
Carlow
Embedded Software Engineer
Dublin
Senior Electronics Engineer
Limerick
Supply Chain Specialist - New Material I
Meath
Senior R&D Engineer
Dublin
Design Assurance Engineer
Galway
Senior Associate Quality Control
Dublin
Senior Regulatory Affairs Specialist
Athlone
Director of R&D
Limerick
QA Operations Specialist
Dublin
Quality Engineer
Athlone
Principal Device Engineer
Dublin
Engineering Business Manager
Dublin
Senior Regulatory Specialist
Cork
Principal Software Engineer
Athlone
Quality Assurance Specialist/Manager
Dublin
Senior Clean Utilities Engineer
Dublin
Principal Design Assurance Engineer
Galway
Senior Research and Development Engineer
Galway
Senior Maintenance Technician
Kilkenny
R&D Engineer
Galway
Continuous Improvement Coach
Limerick
Senior Research Scientist
Galway
Director of R&D
Clare
Quality Assurance Team Lead
Cork
Injection Molding Engineer
North Leinster
Project Manager
Kildare
Software Design Assurance Engineer
Dublin
Senior Research & Development Engine
Limerick
Project Engineer
Cork
Senior Associate QC (QC Sample Managemen
Dublin
Product Development Engineer
Galway
Business Development Manager (Hospitals)
Cork
R&D Manager
Galway
Quality Specialist
Clare
Senior R&D Engineer
Galway
Engineering Support Specialist
Louth
Advanced Technologies R&D Manager
Clare
Supplier Quality Engineer
Galway
Principal Process Equipment Engineer
Dublin South
Senior Process Engineer
Dublin
Facilities Engineer
Wexford
Senior R&D Engineer
Galway
Senior R&D Engineer
Galway
Senior R&D Manager - Lifecycle Manag
Galway
Sales/Customer Service Administrator
Clonmel
Manufacturing Engineer
Galway
Calibration Technician
Republic of Ireland
Clinical Trial Manager
Republic of Ireland
Senior Equipment Design Engineer
Dublin
Senior Quality Systems Engineer
Galway
R&D Manager
Galway
Continuous Improvement Coach
Limerick
Sr Principal R&D Engineer
Galway
Senior QC Associate
Dublin
QA Manager
Canada
Senior R&D Engineer
Clare
Senior R&D Engineer
Clare
Quality Manager
Dublin
Director of Regulatory Affairs
Galway
R&D Manager
Connaught
Senior Project Engineer
Cavan
Senior R&D Engineer
Galway
Quality Specialist
Tipperary
Senior Product Development Engineer
Galway
Senior Regulatory Affairs Specialist
Westmeath
CTO
Galway
Senior Electronic Engineer
Dublin
Supplier Quality Engineer
Galway
Quality Technician
Dublin
Equipment Engineer (Syringe filling)
Dublin
Senior Regulatory Affairs Manager
Galway
Accreditation Manager
Republic of Ireland
Technical Life Cycle & Engineering M
Galway
Supply Chain Specialist - SAP Master Dat
Meath
Sterilisation Manager
Tipperary
Manufacturing Technician
Clare
Mechanical Technician
Carlow
Shift Technician (Injection Moulding)
Kildare
Regulatory Affairs Manager - Senior
Galway
Quality Engineer
Galway
Senior R&D Engineer
Galway
Distribution Manager (Chemicals)
Dublin
R&D Director
Galway
Principal Design and Development Enginee
Galway
Electronic Engineering
Dublin
Senior Design Assurance Engineer
Galway
Senior Process Engineer - DP or DS
Dublin
Production Operator
Meath
R&D Engineer
Galway
Process Development Engineer
Galway
Senior R&D Manager - Lifecycle Manag
Galway
Senior Project Engineer
Dublin
Product Development Engineer II
Athlone
Technical Life Cycle & Engineering M
Galway
Strategy Associate Director / Director -
Dublin
Project Engineer
Clare
Senior R&D Engineer
Galway
Continuous Improvement Coach
Limerick
Senior Quality Assurance Technical Suppo
Dublin
Quality Engineer - Supplier
Galway
Project Engineer - Senior
Cavan
Senior Product Development Engineer
Galway
R&D Engineer
Dublin
R&D Director
Galway
Quality Assurance Specialist (shift)
Carlow
Quality Engineer
Athlone
R&D Manager
Connaught
Consultant




Search Results for Downstream Process
Job Title. Location Salary Actions

Advanced Technologies Manager

Job title: Advanced Technologies R&D Manager Location: Ballybrit, Galway Benefits: Competitive salary, 13% yearly bonus, share options, pension and Healthcare. Company: My client is an emerging leader in Neurovascular care in the Medical Device industry. Located in a European hub for the Medical Device industry my client works closely with physicians from around the world to develop devices used in the endovascular treatment of strokes. Role: As an Advanced Technologies R&D Manager you will be responsible for providing t...

Location: Galway, Galway City,
Advanced Technologies Manager 		Galway Not Disclosed
Subscribe RSS feed for this search

Downstream Process Career Profile

Downstream Processing Engineer

Downstream processing the isolation and purification of the biotech product, which has been producted in the fermentation (upstream stage). As the desired product is usually secreted into the medium, the first step is normally filtration or centrifugation. Liquid chromatography and / or membrane filtration is then used to separate the desired protein product from the other proteins present in the mixture, in order to concentrate the desired biopharmaceutical product.


Key Responsibilities of the Downstream Processing Engineer

  • Participate in facility and process design of a multi-product biopharmaceutical manufacturing platform.
  • Play a role in commissioning and start-up of the biotech facility.
  • Play a role in developing and predicting processing strategies and throughputs for the various products for the site biotech business.
  • Provide day-to-day bioprocess engineering support to downstream manufacturing operations.
  • Initiate facility and equipment upgrades to improve plant productivity and throughput.
  • Facilitate the introduction of new products with associated new equipment and ensure the bioprocessing at the site stays current with emerging processing and equipment trends.
Required Qualifications & Experience
  • A degree-level or higher qualification in Biochemical/Chemical Engineering or a related discipline.
  • Knowledge of the downstream biopharmaceutical unit operations involved with bioreactor design and control, Sterilisation in Place (SIP) / Cleaning in Place (CIP), filtration etc.
  • Experience in either design or commissioning of a mammalian cell-based biopharmaceutical manufacturing plant.
  • Operations experience in purification or related bioprocess manufacturing experience in an established biotech production operation.