I'm looking for...
close

Did you know that your Internet Explorer is out of date?

To get the best possible experience using our website we recommend that you upgrade to a newer version or download another web browser.
A list of the most popular web browsers can be found below. Just click on the icons to get to the download page.

crome
Google Chrome		 IE
Internet Explorer		 firefox
Mozilla Firefox		 opera
Opera

Your browser will need to close to complete the installation and you will need to manually reload the site when finished
Hot Science Jobs
Senior Operations Engineer
Galway
Design Assurance Engineer
Galway
Senior R&D Engineer
Galway
Product Development Technician II
Galway
Project Manager
Kildare
Senior R&D Engineer
Galway
Quality Engineer
Athlone
Engineering Support Specialist
Louth
Product Specialist (Endoscopy)
Dublin
Senior R&D Manager - Lifecycle Manag
Galway
Senior Manufacturing Engineer
Galway City
Quality Engineer
Athlone
CTO
Dublin
Graduate Occupational Hygiene Consultant
Kildare
Senior R&D Engineer
Galway
Industrial Designer
Galway
Technical Support Specialist - Drug Subs
Louth
Injection Moulding Engineer
Athlone
Maintenance & Reliability Technician
Limerick
Purchasing & Planning Manager
Wexford
Senior R&D Engineer
Galway
Documentation Specialist
Louth
R&D Manager
Galway
Validation Engineer
Carlow
Principal R&D Engineer
Galway
Senior Product Development Engineer
Galway
Commercial Attribute Science Scientist
Dublin
Electronic Engineer
Dublin
R&D Manager
Connaught
QC Bioanalytical Sciences - Senior Assoc
Dublin
Senior Regulatory Affairs Manager
Galway
Senior R&D Engineer
Galway
Documentation Specialist
Louth
Advanced Technologies Manager
Galway
Quality Specialist (hybrid)
Tipperary
Project Manager
Galway
R&D Engineer
Galway
Quality Engineer
Galway
Product Development Engineer
Dublin
R&D Engineer
Galway
Principal R&D Engineer
Galway
R&D Engineer
Galway
Senior Research and Development Engineer
Galway
R&D Engineer
Galway
Senior R&D Engineer
Dublin
Product Development Engineer
Dublin
Senior QA Associate (24/7 Shift)
Dublin
Quality Technician
Dublin
R&D Engineer
Galway
Principal R&D Engineer
Dublin
R&D Manager
Connaught
Principal Quality Engineer
Galway
Senior Quality Engineer
Galway
Product Development Engineer
Galway
Senior Product Development Engineer
Galway
CTO
Galway
R&D Engineer
Galway
Product Development Manager
Galway
Senior R&D Engineer
Galway
Injection Molding Engineer
North Leinster
Staff Systems Engineer
Limerick
Project Manager - R&D
Galway
Reg Affairs Specialist
Connaught
Manufacturing Technician
Clare
Senior Quality Assurance Specialist (hyb
Dublin
Business Development Manager (Pharma &am
Republic of Ireland
Senior Product Development Engineer
Galway
Quality Manager
Galway
Staff R&D Engineer
Limerick
Senior Electronic Engineer - Regulated M
Galway
Design Assurance Engineer
Galway
Quality Engineer
Galway
Senior Electrical Engineer
Galway
Quality Manager
Galway
Sr Principal R&D Engineer
Galway
Product Development Engineer
Galway
R&D Manager
Connaught
Senior Electronic Engineer
Dublin
Injection Moulding Engineer
Athlone
Process Development Engineer
Galway
Senior QC Associate
Dublin
R&D Technician II
Galway
Senior Project Engineer
Dublin
Sr Electrical Engineer
Galway
Senior R&D Engineer
Galway
R&D Engineer
Dublin
Design Assurance Program Manager
Galway
Electrical Technician
Limerick
Principal Engineer
Dublin
Embedded Software Engineer
Dublin
Senior R&D Manager - Lifecycle Manag
Galway
Principal Software Engineer
Athlone
Project Manager Design Assurance
Galway
Inside Sales Representative (IVD Divisio
Kildare
QA Engineer
Leitrim
Director of Quality Engineering
Limerick
Senior Operations Engineer
Galway
Senior Quality Engineer
Dublin
Purchasing & Planning Manager
Wexford
Quality Manager
Dublin
Senior R&D Manager
Athlone
R&D Manager
Galway
Senior Equipment Design Engineer
Dublin
Senior R&D Engineer
Galway
Senior Equipment Design Engineer
Dublin
Senior Design Assurance Engineer
Galway
Senior Manufacting Engineer
Republic of Ireland
R&D Director
Galway
Project Engineer
Republic of Ireland
R&D Director
Galway
R&D Engineer
Dublin
Responsible Person (RP)
Republic of Ireland
Engineering Manager
Galway
Product Development Engineer
Dublin
Senior Validation Engineer - HVAC
Dublin
QA Manager
Canada
Senior R&D Engineer-New Product Deve
Westmeath
Senior R&D Engineer
Galway
Technical Life Cycle & Engineering M
Galway
Director of R&D
Limerick
Principal R&D Engineer
Galway
R&D Engineer
Galway
Process Engineer Specialist
Carlow
Process Chemist
Limerick
Senior Quality Assurance Specialist
Cork
Injection Molding Engineer
North Leinster
Quality Assurance Specialist (shift)
Carlow
Senior Process Engineer
Longford
Senior Quality Engineer
Leitrim
R&D Manager
Dublin
Senior Quality Engineer
Dublin
Quality Assurance Specialist (hybrid)
Dublin
Calibration Technician
Republic of Ireland
R&D Engineer
Galway
R&D Program Manager
Dublin
Senior R&D Engineer
Galway
Quality Engineer
Galway
Quality Specialist
Clare
Senior R&D Engineer
Clare
Shift Technician (Injection Moulding)
Kildare
Validation Engineer
Republic of Ireland
Supply Chain Project Manager (hybrid)
Dublin
Senior R&D Engineer
Dublin
R&D Manager
Galway
Business Development Representative-Cali
Republic of Ireland
Project Engineer
Cork
Analytical Chemist
Tipperary
Application Software Engineer
Galway
Principal Process Equipment Engineer
Dublin South
Quality Assurance Specialist (Logistics)
Dublin
Senior Regulatory Affairs Specialist
Athlone
Quality Engineer
Galway
Senior R&D Engineer
Galway
Senior R&D Engineer
Galway
Senior Automation Engineer
Dublin
Electronic Engineer
Dublin
Senior Maintenance Technician
Roscommon
R&D Director
Galway
Mechanical Technician
Carlow
Senior Reg Affairs Specialist - Post Mar
Galway
Injection Molding Engineer
North Leinster
R&D Engineer
Galway
Quality Manager - Medical Devices
Limerick City
Senior R&D Engineer
Dublin
Senior Quality Engineer
Dublin
Product Development Technician II
Galway
Senior R&D Engineer
Clare
Electronic Engineer
Dublin
Senior Regulatory Affairs Specialist
Athlone
Quality Assurance Specialist (shift)
Carlow
Senior Design Assurance Engineer
Galway
Advanced Technologies R&D Manager
Clare
Regulatory Affairs Specialist
Cork
Senior QC Technical Services - Equipment
Dublin
R&D Engineer
Galway
R&D Engineer
Clare
Senior Regulatory Affairs Manager
Galway
Senior Design Assurance Engineer
Galway
Continuous Improvement Coach
Limerick
Supplier Quality Engineer
Galway
Biomedical Engineer
Dublin
Senior Quality Engineer
Leitrim
R&D Engineer
Galway
Process Engineer
Galway
Senior Quality Engineer
Dublin
Learning Systems Lead
Limerick
R&D Manager
Connaught
Senior Regulatory Specialist
Cork
Quality Systems Manager
Dublin
Senior Design Assurance Engineer
Galway
Business Excellence Lead (Manufacturing)
Wexford
Project Manager - R&D
Galway
Warehouse Operator
Meath
Senior R&D Engineer
Galway
R&D Manager
Athlone
Senior Equipment Design Engineer
Dublin
Regulatory Affairs Manager - Senior
Galway
Product Development Engineer II
Athlone
Senior Electronic Engineer
Dublin
Sterilisation Manager
Tipperary
Senior Product Development Engineer
Galway
R&D Manager
Athlone
Quality Manager
Galway
Director of Regulatory Affairs
Galway
Maintenance & Reliability Technician
Limerick
Cleaning Validation Engineer
Republic of Ireland
Operations Engineer
Galway
Project Manager
Kildare
Senior R&D Engineer
Galway
Quality Engineer
Galway
Quality Assurance Team Lead
Cork
Quality Specialist
Tipperary
Injection Moulding Engineer
Athlone
R&D Director
Galway
Senior Design Assurance Engineer
Athlone
R&D Manager
Galway
Senior Associate Quality Control (Shift)
Dublin
Project Manager (hybrid)
Dublin
R&D Manager
Galway
Design Assurance Engineer
Clare
Engineering Business Manager
Dublin
Senior QC Associate (Bioassay)
Dublin
Technical Life Cycle & Engineering M
Galway
Consultant




Search Results for Downstream Process
Job Title. Location Salary Actions

Advanced Technologies Manager

Job title: Advanced Technologies R&D Manager Location: Ballybrit, Galway Benefits: Competitive salary, 13% yearly bonus, share options, pension and Healthcare. Company: My client is an emerging leader in Neurovascular care in the Medical Device industry. Located in a European hub for the Medical Device industry my client works closely with physicians from around the world to develop devices used in the endovascular treatment of strokes. Role: As an Advanced Technologies R&D Manager you will be responsible for providing t...

Location: Galway, Galway City,
Advanced Technologies Manager 		Galway Not Disclosed
Subscribe RSS feed for this search

Downstream Process Career Profile

Downstream Processing Engineer

Downstream processing the isolation and purification of the biotech product, which has been producted in the fermentation (upstream stage). As the desired product is usually secreted into the medium, the first step is normally filtration or centrifugation. Liquid chromatography and / or membrane filtration is then used to separate the desired protein product from the other proteins present in the mixture, in order to concentrate the desired biopharmaceutical product.


Key Responsibilities of the Downstream Processing Engineer

  • Participate in facility and process design of a multi-product biopharmaceutical manufacturing platform.
  • Play a role in commissioning and start-up of the biotech facility.
  • Play a role in developing and predicting processing strategies and throughputs for the various products for the site biotech business.
  • Provide day-to-day bioprocess engineering support to downstream manufacturing operations.
  • Initiate facility and equipment upgrades to improve plant productivity and throughput.
  • Facilitate the introduction of new products with associated new equipment and ensure the bioprocessing at the site stays current with emerging processing and equipment trends.
Required Qualifications & Experience
  • A degree-level or higher qualification in Biochemical/Chemical Engineering or a related discipline.
  • Knowledge of the downstream biopharmaceutical unit operations involved with bioreactor design and control, Sterilisation in Place (SIP) / Cleaning in Place (CIP), filtration etc.
  • Experience in either design or commissioning of a mammalian cell-based biopharmaceutical manufacturing plant.
  • Operations experience in purification or related bioprocess manufacturing experience in an established biotech production operation.